cinanserin hydrochloride Search Results


92
Tocris cinanserin hydrochloride
(A) Structural formula of 5-HT and BJ-1108. (B) After incubation with 5-HT for 3 days, the newly formed blood vessel branches on the 13-day-old chick CAM were counted. Data represent the mean ± S.E.M. of at least seven chick embryos. * P <0.05, compared with the untreated control group, (C) HUVECs in Matrigel-coated plates were treated with 5-HT for 14 h, and digital images were then taken under the microscope. (D) Migration pattern of HUVECs after treatment with VEGF or 5-HT for 5 h. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. (E) Tube formation of HUVECs treated with 5-HT for 14 h in the absence or presence of 0.1 μM cyanopindolol (CYPD), <t>Cinanserin</t> (CISN), or SB269970 was quantitated by measuring tube length on the digital images. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. # P <0.05 compared with the 5-HT-stimulated group.
Cinanserin Hydrochloride, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cinanserin+hydrochloride/Cinanserin+hydrochloride/pmc04732985-41-4-12
Average 92 stars, based on 1 article reviews
cinanserin hydrochloride - by Bioz Stars, 2026-11
92/100 stars
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93
Tocris cinanserin hcl
(A) Structural formula of 5-HT and BJ-1108. (B) After incubation with 5-HT for 3 days, the newly formed blood vessel branches on the 13-day-old chick CAM were counted. Data represent the mean ± S.E.M. of at least seven chick embryos. * P <0.05, compared with the untreated control group, (C) HUVECs in Matrigel-coated plates were treated with 5-HT for 14 h, and digital images were then taken under the microscope. (D) Migration pattern of HUVECs after treatment with VEGF or 5-HT for 5 h. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. (E) Tube formation of HUVECs treated with 5-HT for 14 h in the absence or presence of 0.1 μM cyanopindolol (CYPD), <t>Cinanserin</t> (CISN), or SB269970 was quantitated by measuring tube length on the digital images. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. # P <0.05 compared with the 5-HT-stimulated group.
Cinanserin Hcl, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cinanserin+hydrochloride/Cinanserin+hydrochloride/10__1016_slash_j__bmc__2008__04__050-182-0-8
Average 93 stars, based on 1 article reviews
cinanserin hcl - by Bioz Stars, 2026-11
93/100 stars
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90
Bristol Myers cinanserin hydrochloride
(A) Structural formula of 5-HT and BJ-1108. (B) After incubation with 5-HT for 3 days, the newly formed blood vessel branches on the 13-day-old chick CAM were counted. Data represent the mean ± S.E.M. of at least seven chick embryos. * P <0.05, compared with the untreated control group, (C) HUVECs in Matrigel-coated plates were treated with 5-HT for 14 h, and digital images were then taken under the microscope. (D) Migration pattern of HUVECs after treatment with VEGF or 5-HT for 5 h. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. (E) Tube formation of HUVECs treated with 5-HT for 14 h in the absence or presence of 0.1 μM cyanopindolol (CYPD), <t>Cinanserin</t> (CISN), or SB269970 was quantitated by measuring tube length on the digital images. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. # P <0.05 compared with the 5-HT-stimulated group.
Cinanserin Hydrochloride, supplied by Bristol Myers, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cinanserin+hydrochloride/cinanserin+hydrochloride/pm09040123-115-40-42
Average 90 stars, based on 1 article reviews
cinanserin hydrochloride - by Bioz Stars, 2026-11
90/100 stars
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N/A
Cinanserin hydrochloride is a 5-HT2 antagonist.
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N/A
Cinanserin hydrochloride (SQ 10643) is a potent, selective and highly affinity 5-HT2 receptor antagonist with a Ki of 41 nM. Cinanserin hydrochloride has a much higher binding affinity for the 5-HT2 than for the 5-HT1
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N/A
Cinanserin hydrochloride is the hydrochloride salt of cinanserin, which is a 5-HT2 antagonist and an inhibitor of GPVI-mediated cell activation. It also acts as an inhibitor of CRP-XL- and collagen-induced Ca2+ release and aggregation. It
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N/A
Cinanserin Hydrochloride(Cat No.:I010214)is a serotonin receptor antagonist that specifically inhibits 5-HT2A receptors. It is primarily used in research to explore its role in modulating serotonin-related pathways and its potential therapeutic effects in neurological and psychiatric
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Image Search Results


(A) Structural formula of 5-HT and BJ-1108. (B) After incubation with 5-HT for 3 days, the newly formed blood vessel branches on the 13-day-old chick CAM were counted. Data represent the mean ± S.E.M. of at least seven chick embryos. * P <0.05, compared with the untreated control group, (C) HUVECs in Matrigel-coated plates were treated with 5-HT for 14 h, and digital images were then taken under the microscope. (D) Migration pattern of HUVECs after treatment with VEGF or 5-HT for 5 h. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. (E) Tube formation of HUVECs treated with 5-HT for 14 h in the absence or presence of 0.1 μM cyanopindolol (CYPD), Cinanserin (CISN), or SB269970 was quantitated by measuring tube length on the digital images. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. # P <0.05 compared with the 5-HT-stimulated group.

Journal: PLoS ONE

Article Title: BJ-1108, a 6-Amino-2,4,5-Trimethylpyridin-3-ol Analog, Inhibits Serotonin-Induced Angiogenesis and Tumor Growth through PI3K/NOX Pathway

doi: 10.1371/journal.pone.0148133

Figure Lengend Snippet: (A) Structural formula of 5-HT and BJ-1108. (B) After incubation with 5-HT for 3 days, the newly formed blood vessel branches on the 13-day-old chick CAM were counted. Data represent the mean ± S.E.M. of at least seven chick embryos. * P <0.05, compared with the untreated control group, (C) HUVECs in Matrigel-coated plates were treated with 5-HT for 14 h, and digital images were then taken under the microscope. (D) Migration pattern of HUVECs after treatment with VEGF or 5-HT for 5 h. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. (E) Tube formation of HUVECs treated with 5-HT for 14 h in the absence or presence of 0.1 μM cyanopindolol (CYPD), Cinanserin (CISN), or SB269970 was quantitated by measuring tube length on the digital images. The bar graph represents the mean ± S.E.M. of at least three independent experiments. * P <0.05, compared with the untreated control group. # P <0.05 compared with the 5-HT-stimulated group.

Article Snippet: Gallein, AZM-475271, Cyanopindolol hemifumarate, Cinanserin hydrochloride, and SB-269970 hydrochloride were purchased from Tocris Bioscience (Tocris House, Bristol, BS110QL, UK).

Techniques: Incubation, Control, Microscopy, Migration